Publications

Peer reviewed publications

[36] V.K. Raghunathan, S.M. Thomasy, P. Strom, B. Yanez-Soto, S.P. Garland, J. Sermeno, C.M. Reilly, C.J. Murphy, Tissue and cellular biomechanics during corneal wound injury and repair, Acta Biomater.  (2017). PUBMED
[35] D.S. Shin, Z. Matharu, J. You, C. Siltanen, T. Vu, V.K. Raghunathan, G. Stybayeva, A.E. Hill, A. Revzin, Sensing Conductive Hydrogels for Rapid Detection of Cytokines in Blood, Advanced healthcare materials 5(6) (2016) 659-64, 627. PUBMED
[34] V.K. Raghunathan, J.T. Morgan, P. Russell, 8. Biomechanics and the aqueous humor outflow pathway, in: P.A. Knepper, J.R. Samples (Eds.), Glaucoma Research and Clinical Advances 2016 to 2018, Kugler Publications, Amsterdam, The Netherlands, 2016, pp. 121-138.
[33] B.C. Leonard, B. Yanez-Soto, V.K. Raghunathan, N.L. Abbott, C.J. Murphy, Species variation and spatial differences in mucin expression from corneal epithelial cells, Exp. Eye Res. 152 (2016) 43-48. PUBMED
[32] M. Ali, V. Raghunathan, J.Y. Li, C.J. Murphy, S.M. Thomasy, Biomechanical relationships between the corneal endothelium and Descemet's membrane, Exp. Eye Res. 152 (2016) 57-70. PUBMED
[31] J. You, V.K. Raghunathan, K.J. Son, D. Patel, A. Haque, C.J. Murphy, A. Revzin, Impact of Nanotopography, Heparin Hydrogel Microstructures, and Encapsulated Fibroblasts on Phenotype of Primary Hepatocytes, ACS Appl Mater Interfaces 7(23) (2015) 12299-308. PUBMED
[30] B. Yanez-Soto, B.C. Leonard, V.K. Raghunathan, N.L. Abbott, C.J. Murphy, Effect of Stratification on Surface Properties of Corneal Epithelial Cells, Invest. Ophthalmol. Vis. Sci. 56(13) (2015) 8340-8. PUBMED
[29] M. Winkler, G. Shoa, S.T. Tran, Y. Xie, S. Thomasy, V.K. Raghunathan, C. Murphy, D.J. Brown, J.V. Jester, A Comparative Study of Vertebrate Corneal Structure: The Evolution of a Refractive Lens, Invest. Ophthalmol. Vis. Sci. 56(4) (2015) 2764-72. PUBMED
[28] V.K. Raghunathan, J.T. Morgan, S.A. Park, D. Weber, B.S. Phinney, C.J. Murphy, P. Russell, Dexamethasone Stiffens Trabecular Meshwork, Trabecular Meshwork Cells, and Matrix, Invest. Ophthalmol. Vis. Sci. 56(8) (2015) 4447-59. PUBMED
[27] V.K. Raghunathan, J.T. Morgan, Y.R. Chang, D. Weber, B. Phinney, C.J. Murphy, P. Russell, Transforming Growth Factor Beta 3 Modifies Mechanics and Composition of Extracellular Matrix Deposited by Human Trabecular Meshwork Cells, ACS Biomaterials Science & Engineering 1(2) (2015) 110-118. JOURNAL
[26] J.T. Morgan, V.K. Raghunathan, Y.R. Chang, C.J. Murphy, P. Russell, The intrinsic stiffness of human trabecular meshwork cells increases with senescence, Oncotarget 6(17) (2015) 15362-74. PUBMED
[25] J.T. Morgan, V.K. Raghunathan, Y.R. Chang, C.J. Murphy, P. Russell, Wnt inhibition induces persistent increases in intrinsic stiffness of human trabecular meshwork cells, Exp. Eye Res. 132 (2015) 174-8. PUBMED
[24] J. Gao, V.K. Raghunathan, B. Reid, D. Wei, R.C. Diaz, P. Russell, C.J. Murphy, M. Zhao, Biomimetic stochastic topography and electric fields synergistically enhance directional migration of corneal epithelial cells in a MMP-3-dependent manner, Acta Biomater. 12(0) (2015) 102-12. PUBMED
[23] S.M. Thomasy, V.K. Raghunathan, M. Winkler, C.M. Reilly, A.R. Sadeli, P. Russell, J.V. Jester, C.J. Murphy, Elastic modulus and collagen organization of the rabbit cornea: epithelium to endothelium, Acta Biomater. 10(2) (2014) 785-91. PUBMED
[22] V.K. Raghunathan, B. Dreier, J.T. Morgan, B.C. Tuyen, B.W. Rose, C.M. Reilly, P. Russell, C.J. Murphy, Involvement of YAP, TAZ and HSP90 in contact guidance and intercellular junction formation in corneal epithelial cells, PLoS One 9(10) (2014) e109811. PUBMED
[21] S.A. Park, L.B. Teixeira, V.K. Raghunathan, J. Covert, R.R. Dubielzig, R.R. Isseroff, M. Schurr, N.L. Abbott, J. McAnulty, C.J. Murphy, Full-thickness splinted skin wound healing models in db/db and heterozygous mice: implications for wound healing impairment, Wound Repair Regen. 22(3) (2014) 368-80. PUBMED
[20] S.A. Park, V.K. Raghunathan, N.M. Shah, L. Teixeira, M.J. Motta, J. Covert, R. Dubielzig, M. Schurr, R.R. Isseroff, N.L. Abbott, J. McAnulty, C.J. Murphy, PDGF-BB does not accelerate healing in diabetic mice with splinted skin wounds, PLoS One 9(8) (2014) e104447. PUBMED
[19] J.T. Morgan, J.A. Wood, N.J. Walker, V.K. Raghunathan, D.L. Borjesson, C.J. Murphy, P. Russell, Human trabecular meshwork cells exhibit several characteristics of, but are distinct from, adipose-derived mesenchymal stem cells, J. Ocul. Pharmacol. Ther. 30(2-3) (2014) 254-66. PUBMED
[18] J.T. Morgan, V.K. Raghunathan, S.M. Thomasy, C.J. Murphy, P. Russell, Robust and artifact-free mounting of tissue samples for atomic force microscopy, BioTechniques 56(1) (2014) 40-2. PUBMED
[17] K.A. Keller, J. Paul-Murphy, E.P. Weber, 3rd, P.H. Kass, S.M. Guzman, S.A. Park, V.K. Raghunathan, K.A. Gustavsen, C.J. Murphy, Assessment of platelet-derived growth factor using A splinted full thickness dermal wound model in bearded dragons (Pogona vitticeps), J. Zoo Wildl. Med. 45(4) (2014) 866-74. PUBMED
[16] F. Gorouhi, N.M. Shah, V.K. Raghunathan, Y. Mohabbati, N.L. Abbott, R.R. Isseroff, C.J. Murphy, Epidermal growth factor-functionalized polymeric multilayer films: interplay between spatial location and bioavailability of EGF, J. Invest. Dermatol. 134(6) (2014) 1757-60. PUBMED
[15] S.P. Garland, R.Y. Wang, V.K. Raghunathan, K.S. Lam, C.J. Murphy, P. Russell, G. Sun, T. Pan, Photopatternable and photoactive hydrogel for on-demand generation of hydrogen peroxide in cell culture, Biomaterials 35(5) (2014) 1762-70. PUBMED
[14] S.P. Garland, C.T. McKee, Y.R. Chang, V.K. Raghunathan, P. Russell, C.J. Murphy, A cell culture substrate with biologically relevant size-scale topography and compliance of the basement membrane, Langmuir 30(8) (2014) 2101-8. PUBMED
[13] Y.R. Chang, V.K. Raghunathan, S.P. Garland, J.T. Morgan, P. Russell, C.J. Murphy, Automated AFM force curve analysis for determining elastic modulus of biomaterials and biological samples, J Mech Behav Biomed Mater 37(0) (2014) 209-18. PUBMED
[12] J. You, S.A. Park, D.S. Shin, D. Patel, V.K. Raghunathan, M. Kim, C.J. Murphy, G. Tae, A. Revzin, Characterizing the effects of heparin gel stiffness on function of primary hepatocytes, Tissue engineering. Part A 19(23-24) (2013) 2655-63. PUBMED
[11] V.K. Raghunathan, J.T. Morgan, B. Dreier, C.M. Reilly, S.M. Thomasy, J.A. Wood, I. Ly, B.C. Tuyen, M. Hughbanks, C.J. Murphy, P. Russell, Role of substratum stiffness in modulating genes associated with extracellular matrix and mechanotransducers YAP and TAZ, Invest. Ophthalmol. Vis. Sci. 54(1) (2013) 378-86. PUBMED
[10] V.K. Raghunathan, C.T. McKee, E.J. Tocce, P.F. Nealey, P. Russell, C.J. Murphy, Nuclear and cellular alignment of primary corneal epithelial cells on topography, J. Biomed. Mater. Res. A 101(4) (2013) 1069-79. PUBMED
[9] V.K. Raghunathan, M. Devey, S. Hawkins, L. Hails, S.A. Davis, S. Mann, I.T. Chang, E. Ingham, A. Malhas, D.J. Vaux, J.D. Lane, C.P. Case, Influence of particle size and reactive oxygen species on cobalt chrome nanoparticle-mediated genotoxicity, Biomaterials 34(14) (2013) 3559-70. PUBMED
[8] V. Raghunathan, C. McKee, W. Cheung, R. Naik, P.F. Nealey, P. Russell, C.J. Murphy, Influence of extracellular matrix proteins and substratum topography on corneal epithelial cell alignment and migration, Tissue engineering. Part A 19(15-16) (2013) 1713-22. PUBMED
[7] B. Dreier, S.M. Thomasy, R. Mendonsa, V.K. Raghunathan, P. Russell, C.J. Murphy, Substratum compliance modulates corneal fibroblast to myofibroblast transformation, Invest. Ophthalmol. Vis. Sci. 54(8) (2013) 5901-7. PUBMED
[6] B. Dreier, V.K. Raghunathan, P. Russell, C.J. Murphy, Focal adhesion kinase knockdown modulates the response of human corneal epithelial cells to topographic cues, Acta Biomater. 8(12) (2012) 4285-94. PUBMED
[5] C.T. McKee, V.K. Raghunathan, P. Russel, C.J. Murphy, Probing Effect of Biophysical Cues on Cell Behavior with Atomic Force Microscopy, Microscopy and Analysis-UK 25(5) (2011) 25-28. LINK
[4] C.T. McKee, V.K. Raghunathan, P.F. Nealey, P. Russell, C.J. Murphy, Topographic modulation of the orientation and shape of cell nuclei and their influence on the measured elastic modulus of epithelial cells, Biophys. J. 101(9) (2011) 2139-46. PUBMED
[3] V.K. Raghunathan, M.H. Grant, E.M. Ellis, Changes in protein expression associated with chronic in vitro exposure of hexavalent chromium to osteoblasts and monocytes: a proteomic approach, J. Biomed. Mater. Res. A 92(2) (2010) 615-25. PUBMED
[2] V.K. Raghunathan, J.N. Tettey, E.M. Ellis, M.H. Grant, Comparative chronic in vitro toxicity of hexavalent chromium to osteoblasts and monocytes, J. Biomed. Mater. Res. A 88(2) (2009) 543-50. PUBMED
[1] V.K. Raghunathan, E.M. Ellis, M.H. Grant, Response to chronic exposure to hexavalent chromium in human monocytes, Toxicol. In Vitro 23(4) (2009) 647-52. PUBMED